Negative Effects of High Glucose Exposure in Human Gonadotropin-Releasing Hormone Neurons

Abstract

Metabolic disorders are often associated with male hypogonadotropic hypogonadism, suggesting that hypothalamic defects involving GnRH neurons may impair the reproductive function. Among metabolic factors hyperglycemia has been implicated in the control of the reproductive axis at central level, both in humans and in animal models. To date, little is known… (More)
DOI: 10.1155/2013/684659

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