Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents.

Abstract

In order to specify the nature of interactions between the analgesic compound nefopam and the glutamatergic system, we examined the effects of nefopam on binding of specific ligands on the three main subtypes ionotropic glutamate receptors: N-methyl-D-aspartate (NMDA), alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA), or quisqualic acid (QA… (More)

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Cite this paper

@article{Verleye2004NefopamBV, title={Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents.}, author={Marc Verleye and Nathalie Andr{\'e} and Isabelle Heulard and Jean-Marie Gillardin}, journal={Brain research}, year={2004}, volume={1013 2}, pages={249-55} }