Nefopam Hydrochloride*: New Analgesic Agent

  title={Nefopam Hydrochloride*: New Analgesic Agent},
  author={Albert Cohen and Cecilia M Hernandez},
  journal={Journal of International Medical Research},
  pages={138 - 143}
Two dose-levels of nefopam hydrochloride (i.e. 30 mg and 60 mg) were compared with two dose-levels of aspirin (i.e. 300 mg and 600 mg) and placebo in 125 male patients having pain associated with muscle disorders. Drugs were given as a single dose and pain intensity and side-effects monitored at thirty minutes and then hourly for four hours. Time-course action of the drugs revealed that aspirin 300 mg failed to achieve statistically significant analgesia at any post-treatment observation… 

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