Nefopam: A Review of its Pharmacological Properties and Therapeutic Efficacy

@article{Heel2012NefopamAR,
  title={Nefopam: A Review of its Pharmacological Properties and Therapeutic Efficacy},
  author={R. Heel and R. Brogden and G. Pakes and T. Speight and G. Avery},
  journal={Drugs},
  year={2012},
  volume={19},
  pages={249-267}
}
  • R. Heel, R. Brogden, +2 authors G. Avery
  • Published 2012
  • Medicine
  • Drugs
  • SummarySynopsis: Nefopam1 is a non-narcotic analgesic not structurally related to other analgesic drugs. It is effective by the oral and parenteral routes, and when appropriate dose ratios were compared in short term studies it was shown to produce analgesia comparable to that with the oral analgesics aspirin, dextropropoxyphene and pentazocine, as well as that with ‘moderate’ doses of parenteral morphine, pethidine and pentazocine. However, when ‘higher’ dose ratios were compared, morphine and… CONTINUE READING
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    References

    SHOWING 1-10 OF 64 REFERENCES
    Nefopam Hydrochloride*: New Analgesic Agent
    • 12
    Nefopam and morphine in man
    • 65
    Oral nefopam and aspirin
    • 10
    Comparison of nefopam and pethidine in postoperative pain.
    • 33
    • PDF
    Gastrointestinal Blood Loss Study with a New Analgesic Compound: Nefopam Hydrochloride
    • B. Baltes
    • Medicine
    • Journal of clinical pharmacology
    • 1977
    • 9