Nefopam: A Review of its Pharmacological Properties and Therapeutic Efficacy
@article{Heel2012NefopamAR, title={Nefopam: A Review of its Pharmacological Properties and Therapeutic Efficacy}, author={R. Heel and R. Brogden and G. Pakes and T. Speight and G. Avery}, journal={Drugs}, year={2012}, volume={19}, pages={249-267} }
SummarySynopsis: Nefopam1 is a non-narcotic analgesic not structurally related to other analgesic drugs. It is effective by the oral and parenteral routes, and when appropriate dose ratios were compared in short term studies it was shown to produce analgesia comparable to that with the oral analgesics aspirin, dextropropoxyphene and pentazocine, as well as that with ‘moderate’ doses of parenteral morphine, pethidine and pentazocine. However, when ‘higher’ dose ratios were compared, morphine and… CONTINUE READING
Figures, Tables, and Topics from this paper
Paper Mentions
88 Citations
Nefopam analgesia and its role in multimodal analgesia: A review of preclinical and clinical studies
- Medicine
- Clinical and experimental pharmacology & physiology
- 2016
- 37
Rediscovery of Nefopam for the Treatment of Neuropathic Pain
- Medicine
- The Korean journal of pain
- 2014
- 48
- PDF
Nefopam and ketoprofen synergy in rodent models of antinociception.
- Chemistry, Medicine
- European journal of pharmacology
- 2008
- 43
Intravenous Nefopam Reduces Postherpetic Neuralgia during the Titration of Oral Medications
- Medicine
- The Korean journal of pain
- 2014
- 8
- PDF
Compartmental pharmacokinetics of nefopam during mild hypothermia.
- Medicine
- British journal of anaesthesia
- 2012
- 11
- PDF
Population pharmacokinetics of nefopam in elderly, with or without renal impairment, and its link to treatment response.
- Medicine
- British journal of clinical pharmacology
- 2014
- 20
References
SHOWING 1-10 OF 64 REFERENCES
Buprenorphine: A Review of its Pharmacological Properties and Therapeutic Efficacy
- Medicine
- Drugs
- 2012
- 173
Controlled Clinical Trial of Oral and Parenteral Nefopam Hydrochloride. A Novel and Potent Analgesic Drug
- Medicine
- Journal of clinical pharmacology
- 1976
- 19
Nefopam Hydrochloride*: New Analgesic Agent
- Medicine
- The Journal of international medical research
- 1976
- 12
Comparison of the Analgesic Dose‐Effect Relationships of Nefopam and Oxycodone in Postoperative Pain
- Medicine
- Acta anaesthesiologica Scandinavica
- 1979
- 20
A Comparison of the Analgesic Effect of Intramuscular Nefopam and Morphine in Patients with Postoperative Pain
- Medicine
- Journal of clinical pharmacology
- 1977
- 33
Comparison of nefopam and pethidine in postoperative pain.
- Medicine
- British journal of anaesthesia
- 1977
- 33
- PDF
Gastrointestinal Blood Loss Study with a New Analgesic Compound: Nefopam Hydrochloride
- Medicine
- Journal of clinical pharmacology
- 1977
- 9