Neem oil limonoids induces p53-independent apoptosis and autophagy.


Azadirachta indica, commonly known as neem, has a wide range of medicinal properties. Neem extracts and its purified products have been examined for induction of apoptosis in multiple cancer cell types; however, its underlying mechanisms remain undefined. We show that neem oil (i.e., neem), which contains majority of neem limonoids including azadirachtin… (More)
DOI: 10.1093/carcin/bgs269


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@article{Srivastava2012NeemOL, title={Neem oil limonoids induces p53-independent apoptosis and autophagy.}, author={Pragya Srivastava and Neelu Yadav and Ravi K. Lella and Andrea Schneider and A Maxwell P Jones and Timothy A Marlowe and Gabrielle Lovett and Kieran L O'Loughlin and Hans Minderman and Raghu Gogada and Dhyan Chandra}, journal={Carcinogenesis}, year={2012}, volume={33 11}, pages={2199-207} }