Needle-free jet injections: dependence of jet penetration and dispersion in the skin on jet power.

@article{SchrammBaxter2004NeedlefreeJI,
  title={Needle-free jet injections: dependence of jet penetration and dispersion in the skin on jet power.},
  author={Joy Schramm-Baxter and Samir Mitragotri},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2004},
  volume={97 3},
  pages={527-35}
}
Jet injection is a needle-free drug delivery method in which a high-speed stream of fluid impacts the skin and delivers drugs. Although a number of jet injectors are commercially available, especially for insulin delivery, a quantitative understanding of the energetics of jet injection is still lacking. Here, we describe the dependence of jet injections into human skin on the power of the jet. Dermal delivery of liquid jets was quantified using two measurements, penetration of a radiolabeled… CONTINUE READING

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