Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule.

@article{Galibert2005NectinlikeP2,
  title={Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule.},
  author={Laurent Galibert and Geoffrey S. Diemer and Zhi Liang Liu and Richard S Johnson and Jeffrey L. Smith and Thierry Walzer and Michael R. Comeau and Charles T. Rauch and Martin F. Wolfson and Rick A Sorensen and Anne-Ren{\'e}e van der Vuurst de Vries and Daniel G. Branstetter and Raymond M Koelling and John K. Scholler and William C. Fanslow and Peter R Baum and Jonathan M.J. Derry and Wei Yan},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 23},
  pages={21955-64}
}
Dendritic cells (DCs) are a phenotypically and functionally heterogenous population of leukocytes with distinct subsets serving a different set of specialized immune functions. Here we applied an in vitro whole cell panning approach using antibody phage display technology to identify cell-surface epitopes specifically expressed on human blood BDCA3(+) DCs. A single-chain antibody fragment (anti-1F12 scFv) was isolated that recognizes a conserved surface antigen expressed on both human BDCA3… CONTINUE READING