Nectin : an adhesion molecule involved in formation of synapses

  title={Nectin : an adhesion molecule involved in formation of synapses},
  author={Akira Mizoguchi and Hiroyuki Nakanishi and Kazushi Kimura and Kaho Matsubara and Kumi Ozaki-Kuroda and Tatsuo Katata and Tomoyuki Honda and Yoshimoto Kiyohara and Kyun Heo and Mikito Higashi and Tomonari Tsutsumi and Satomi Sonoda and Chizuka Ide and Yoshimi Takai},
he nectin–afadin system is a novel cell–cell adhesion system that organizes adherens junctions cooperatively with the cadherin–catenin system in epithelial cells. Nectin is an immunoglobulin-like adhesion molecule, and afadin is an actin filament–binding protein that connects nectin to the actin cytoskeleton. Nectin has four isoforms (-1, -2, -3, and -4). Each nectin forms a homo-cis-dimer followed by formation of a homo-trans-dimer, but nectin-3 furthermore forms a hetero-trans-dimer with… CONTINUE READING


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Imaging synaptic vesicle

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