Necrotoxic Escherichia coli (NTEC): two emerging categories of human and animal pathogens.

  title={Necrotoxic Escherichia coli (NTEC): two emerging categories of human and animal pathogens.},
  author={J De Rycke and A Milon and E Oswald},
  journal={Veterinary research},
  volume={30 2-3},
  • J De Rycke, A Milon, E Oswald
  • Published 1999 in Veterinary research
Necrotoxic Escherichia coli (NTEC) were originally defined as strains of E. coli producing a toxin called cytotoxic necrotising factor (CNF). Two types of CNF have been identified, each of them being genetically linked to several other specific virulence markers, a situation that allows the definition of two distinct homogeneous categories of NTEC called NTEC-1 and NTEC-2. CNF1 and CNF2 are highly homologous holoproteins containing 1,014 amino acids that exert both lethal and necrotic… CONTINUE READING


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