Necrosis in yeast

  title={Necrosis in yeast},
  author={Tobias Eisenberg and Didac Carmona-Guti{\'e}rrez and Sabrina Buettner and Nektarios Tavernarakis and Frank Madeo},
Necrosis was long regarded as an accidental cell death process resulting from overwhelming cellular injury such as chemical or physical disruption of the plasma membrane. Such a definition, however, proved to be inapplicable to many necrotic scenarios. The discovery that genetic manipulation of several proteins either protected or enhanced necrotic cell death argued in favor of a regulated and hence programmed process, as it is the case for apoptosis. For more than a decade, yeast has served as… CONTINUE READING
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