Necroptosis: an emerging form of programmed cell death.

@article{Wu2012NecroptosisAE,
  title={Necroptosis: an emerging form of programmed cell death.},
  author={Wei Wu and Peng Liu and Jianyong Li},
  journal={Critical reviews in oncology/hematology},
  year={2012},
  volume={82 3},
  pages={
          249-58
        }
}
Necrosis plays an important role in multiple physiological and pathological processes. Recently, a relatively new form of necrosis has been characterized as "necroptosis". Morphologically, necroptosis exhibits the features of necrosis; however, necroptosis exhibits a unique signaling pathway that requires the involvement of receptor interaction protein kinase 1 and 3 (RIP1 and RIP3) and can be specifically inhibited by necrostatins. Necroptosis has been found to contribute to the regulation of… Expand
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