Necessity of amoxicillin clavulanic acid in addition to prednisolone in mild-to-moderate COPD exacerbations

@inproceedings{BrusseKeizer2014NecessityOA,
  title={Necessity of amoxicillin clavulanic acid in addition to prednisolone in mild-to-moderate COPD exacerbations},
  author={Marjolein Gj Brusse-Keizer and P D L P M Vandervalk and Ron Hendrix and Huib A. M. Kerstjens and Job van der Palen},
  booktitle={BMJ open respiratory research},
  year={2014}
}
BACKGROUND The effectiveness of antibiotics in chronic obstructive pulmonary disease (COPD) exacerbations is still a matter of debate, especially in outpatients with an intermediate probability of bacterial infection. METHODS In this study, 35 COPD outpatients diagnosed by their chest physician with moderately severe COPD exacerbation, but without pneumonia, were randomised in a double blind, placebo-controlled study. Patients had one or two of the following characteristics: a positive Gram's… CONTINUE READING
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