Nebulized versus intravenous morphine titration for the initial treatment of severe acute pain in the emergency department: study protocol for a multicenter, prospective randomized and controlled trial, CLIN-AEROMORPH

@inproceedings{Lvovschi2019NebulizedVI,
  title={Nebulized versus intravenous morphine titration for the initial treatment of severe acute pain in the emergency department: study protocol for a multicenter, prospective randomized and controlled trial, CLIN-AEROMORPH},
  author={Virginie Eve Lvovschi and J. Michael Joly and Nicolas Lemaire and Maxime Maignan and Pauline Canavaggio and Anne-Marie M. Leroi and M P Tavolacci and Luc-Marie Joly},
  booktitle={Trials},
  year={2019}
}
BACKGROUND Intravenous morphine titration (IVMT) is the French gold standard for opioid treatment in the emergency department (ED). Nebulized morphine titration (NMT) may represent an alternative without venous access, but it has not been adequately studied in adults. We test the hypothesis that NMT is at least as effective as IVMT to initially manage severe acute pain in the ED. METHODS/DESIGN We designed a multicenter (10 French EDs), single-blind, randomized and controlled trial. Adults… CONTINUE READING
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