Nebulized ceftazidime and amikacin in ventilator-associated pneumonia caused by Pseudomonas aeruginosa.

@article{Lu2011NebulizedCA,
  title={Nebulized ceftazidime and amikacin in ventilator-associated pneumonia caused by Pseudomonas aeruginosa.},
  author={Qin Lu and Jianxin Yang and Zhihai Liu and Claudia Guti{\'e}rrez and Guy Aymard and Jean-Jacques Rouby},
  journal={American journal of respiratory and critical care medicine},
  year={2011},
  volume={184 1},
  pages={106-15}
}
RATIONALE In experimental pneumonia, nebulization of antibiotics provides high lung tissue concentrations and rapid bacterial killing. OBJECTIVES To assess the efficacy and safety of nebulized ceftazidime and amikacin in ventilator-associated pneumonia caused by Pseudomonas aeruginosa. METHODS Forty patients with ventilator-associated pneumonia caused by Pseudomonas aeruginosa were included in a randomized comparative phase II trial. Twenty patients infected with susceptible or intermediate… CONTINUE READING