Near-unity nuclear polarization with an open-source 129Xe hyperpolarizer for NMR and MRI.

  title={Near-unity nuclear polarization with an open-source 129Xe hyperpolarizer for NMR and MRI.},
  author={Panayiotis Nikolaou and Aaron M. Coffey and Laura L. Walkup and Brogan M. Gust and Nicholas H. Whiting and Hayley Newton and Scott Barcus and I. A. Muradyan and Mikayel Dabaghyan and Gregory D Moroz and Matthew S. Rosen and S. Patz and Michael J Barlow and Eduard Y Chekmenev and Boyd M Goodson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={110 35},
The exquisite NMR spectral sensitivity and negligible reactivity of hyperpolarized xenon-129 (HP(129)Xe) make it attractive for a number of magnetic resonance applications; moreover, HP(129)Xe embodies an alternative to rare and nonrenewable (3)He. However, the ability to reliably and inexpensively produce large quantities of HP(129)Xe with sufficiently high (129)Xe nuclear spin polarization (P(Xe)) remains a significant challenge--particularly at high Xe densities. We present results from our… CONTINUE READING


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