Near-normoglycaemia and development of neuropathy: a 24-year prospective study from diagnosis of type 1 diabetes

@article{Ziegler2015NearnormoglycaemiaAD,
  title={Near-normoglycaemia and development of neuropathy: a 24-year prospective study from diagnosis of type 1 diabetes},
  author={D. Ziegler and M. Behler and Maria Schroers-Teuber and M. Roden},
  journal={BMJ Open},
  year={2015},
  volume={5}
}
Objective Complete prevention of diabetic neuropathies has not been previously demonstrated. We sought to determine whether long-term near-normoglycaemia maintained from the diagnosis of type 1 diabetes is associated with polyneuropathy and cardiac autonomic dysfunction. Design Prospective observational study over 24 years. Setting Ambulatory care. Participants 32 newly diagnosed patients with type 1 diabetes aged 20.3±1.0 years, duration of diabetes 2.7±0.3 weeks. Intervention Insulin therapy… Expand
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