Near-infrared spectroscopy measurements of cerebral blood flow and oxygen consumption following hypoxia-ischemia in newborn piglets.

@article{Tichauer2006NearinfraredSM,
  title={Near-infrared spectroscopy measurements of cerebral blood flow and oxygen consumption following hypoxia-ischemia in newborn piglets.},
  author={Kenneth M Tichauer and Derek W Brown and Jennifer A. Hadway and Ting-Yim Lee and Keith S. St. Lawrence},
  journal={Journal of applied physiology},
  year={2006},
  volume={100 3},
  pages={850-7}
}
Impaired oxidative metabolism following hypoxia-ischemia (HI) is believed to be an early indicator of delayed brain injury. The cerebral metabolic rate of oxygen (CMRO2) can be measured by combining near-infrared spectroscopy (NIRS) measurements of cerebral blood flow (CBF) and cerebral deoxy-hemoglobin concentration. The ability of NIRS to measure changes in CMRO2 following HI was investigated in newborn piglets. Nine piglets were subjected to 30 min of HI by occluding both carotid arteries… CONTINUE READING

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