Near-infrared photoactivatable control of Ca2+ signaling and optogenetic immunomodulation


The application of current channelrhodopsin-based optogenetic tools is limited by the lack of strict ion selectivity and the inability to extend the spectra sensitivity into the near-infrared (NIR) tissue transmissible range. Here we present an NIR-stimulable optogenetic platform (termed 'Opto-CRAC') that selectively and remotely controls Ca(2… (More)
DOI: 10.7554/eLife.10024


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