Near-infrared oximetry of the brain

@article{Madsen1999NearinfraredOO,
  title={Near-infrared oximetry of the brain},
  author={Per Lav Madsen and Niels H Secher},
  journal={Progress in Neurobiology},
  year={1999},
  volume={58},
  pages={541-560}
}
Near-infrared (IR) light easily penetrates biological tissue, and the information offered by in vivo spectroscopy of cerebral oxygenation is detailed and comes with a high temporal resolution. Near-IR light spectroscopy (NIRS) reflects cerebral oxygenation during arterial hypotension, hypoxic hypoxaemia and hypo- and hypercapnia. As determined by dual-wavelength NIRS, the cerebral O2 saturation integrates the arterial O2 content and the cerebral perfusion, and as established for skeletal muscle… Expand

Paper Mentions

Interventional Clinical Trial
The purpose of this study is to determine whether brain oxygenation measured by cerebral oximeter has an impact on neurocognitive dysfunction.  
ConditionsPostoperative Cognitive Dysfunction, Post-Operative Delirium
InterventionProcedure
Observational Clinical Trial
Due to the small size of infants and the use of bypass machines, physicians have difficulty assessing whether the infant's brain and body is getting enough oxygen during heart surgery… Expand
ConditionsHypoplastic Left Heart, Surgery
Near-Infrared Spectroscopy
Cerebral oximetry uses transcranial near-infrared spectroscopy (NIRS) to evaluate changes in cerebral oxygenation noninvasively and continuously. Its operation relies on two basic principles. First,Expand
4 Near-Infrared Spectroscopy
Near infrared spectroscopy (NIRS) is an imaging technique used in both clinical and emergency medicine, as well as in research laboratories to quantify and measure the oxygenation status of humanExpand
Near infrared spectroscopy.
TLDR
NIRS technology makes it possible to apply critical safety thresholds with regards to cerebral tissue saturation in order to avoid dangerously low levels with the primary goal being to reduce mortality rates and cognitive deficits due to cerebral hypoxemia. Expand
Near-infrared spectroscopy in evaluation of cerebral oxygenation during vasovagal syncope.
TLDR
Results of the examination have shown that the changes in cerebral oxygenation measured by the NIRS technique are distinctly visible before the syncope, and a gradual decrease of oxyhaemoglobin followed by its sudden drop was observed in all the VVS patients. Expand
Noninvasive measurement of cerebral hemoglobin oxygen saturation using two near infrared spectroscopy approaches.
TLDR
Comparisons of forehead tissue oxygenation index (TOI) with the calculated SvO2 during venous occlusion in 16 adult volunteers using a clinical two-channel SRS oximeter confirmed that cerebral cortex hemoglobin oxygen saturation, measured directly by the SRS method, reflects predominantly the saturation of the intracranial venous compartment of circulation. Expand
Usefulness of Cerebral Oximetry in TBI by NIRS
TLDR
This paper summarizes the usefulness of monitoring cerebral oximetry by near-infrared spectroscopy in patients with traumatic brain injury, taking into account the advantages and the disadvantages of this technique. Expand
Interference of Cerebral Near-Infrared Oximetry in Patients with Icterus
TLDR
In 48 patients undergoing orthotopic liver transplantation, bilirubin dampens the spectrophotometry-determined cerebral oxygen saturation at 733 and 809 nm, suggesting that tissue pigmentation deposits also absorb light. Expand
Tissue Oxygen Index: Thresholds for Cerebral Ischemia Using Near-Infrared Spectroscopy
TLDR
A drop in TOI is defined that can be adopted as a threshold for severe cerebral ischemia with high sensitivity and specificity and thus improve the clinical use of near infrared spectroscopy. Expand
Principles, techniques, and limitations of near infrared spectroscopy.
TLDR
NIRS is a noninvasive and relatively low-cost optical technique that is becoming a widely used instrument for measuring tissue O2 saturation, changes in hemoglobin volume and, indirectly, brain/muscle blood flow and muscle O2 consumption. Expand
Capillary-Oxygenation-Level-Dependent Near-Infrared Spectrometry in Frontal Lobe of Humans
TLDR
Results show that NIRS is an adequate cerebral capillaryoxygenation-level-dependent (COLD) measure during manipulation of cerebral blood flow or inspired oxygen tension, or both, and suggest that motor performance correlates with the frontal lobe COLD signal. Expand
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