Near-infrared emitting fluorophore-doped calcium phosphate nanoparticles for in vivo imaging of human breast cancer.

@article{Altinolu2008NearinfraredEF,
  title={Near-infrared emitting fluorophore-doped calcium phosphate nanoparticles for in vivo imaging of human breast cancer.},
  author={Erhan I Altinoğlu and Timothy J Russin and James M Kaiser and Brian M Barth and Peter C. Eklund and Mark Kester and James H. Adair},
  journal={ACS nano},
  year={2008},
  volume={2 10},
  pages={2075-84}
}
Early detection is a crucial element for the timely diagnosis and successful treatment of all human cancers but is limited by the sensitivity of current imaging methodologies. We have synthesized and studied bioresorbable calcium phosphate nanoparticles (CPNPs) in which molecules of the near-infrared (NIR) emitting fluorophore, indocyanine green (ICG), are embedded. The ICG-CPNPs demonstrate exceptional colloidal and optical characteristics. Suspensions consisting of 16 nm average diameter… CONTINUE READING

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