Near-Infrared Investigations of Novel Anti-HIV Tenofovir Liposomes

  title={Near-Infrared Investigations of Novel Anti-HIV Tenofovir Liposomes},
  author={Ahmed Samir Zidan and Crystal B Spinks and Joseph Fortunak and Muhammad J. Habib and Mansoor A. Khan},
  journal={The AAPS Journal},
Near-infrared (NIR) approaches is considered one of the most well-studied process analyzers evolving from the process analytical technology initiatives. The objective of this study was to evaluate NIR spectroscopy and imaging to assess individual components within a novel tenofovir liposomal formulation. By varying stearylamine, as a positive charge imparting agent, five batches were prepared by the thin film method. Each formulation was characterized in terms of drug entrapment efficiency… CONTINUE READING
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