Neandertal origin of genetic variation at the cluster of OAS immunity genes.

@article{Mendez2013NeandertalOO,
  title={Neandertal origin of genetic variation at the cluster of OAS immunity genes.},
  author={Fernando Luis Mendez and Joseph Watkins and Michael F. Hammer},
  journal={Molecular biology and evolution},
  year={2013},
  volume={30 4},
  pages={
          798-801
        }
}
Analyses of ancient DNA from extinct humans reveal signals of at least two independent hybridization events in the history of non-African populations. To date, there are very few examples of specific genetic variants that have been rigorously identified as introgressive. Here, we survey DNA sequence variation in the OAS gene cluster on chromosome 12 and provide strong evidence that a haplotype extending for ~185 kb introgressed from Neandertals. This haplotype is nearly restricted to Eurasians… CONTINUE READING
Highly Cited
This paper has 28 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 20 references

A draft sequence of the Neandertal genome.

Science • 2010
View 3 Excerpts
Highly Influenced