Neamphamide B, new cyclic depsipeptide, as an anti-dormant mycobacterial substance from a Japanese marine sponge of Neamphius sp.
@article{Yamano2012NeamphamideBN, title={Neamphamide B, new cyclic depsipeptide, as an anti-dormant mycobacterial substance from a Japanese marine sponge of Neamphius sp.}, author={Yoshiwo Yamano and Masayoshi Arai and Motomasa Kobayashi}, journal={Bioorganic \& medicinal chemistry letters}, year={2012}, volume={22 14}, pages={ 4877-81 } }
29 Citations
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Two new cyclic depsipeptides, pipecolidepsins A and B, have been isolated from the sponge Homophymia lamellosa collected off the coast of Madagascar and displayed cytotoxic activity against a panel of different human tumor cell lines.
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Evidence that viomellein and xanthomegnin did not directly bind to plasmid DNA suggests its anti-mycobacterial activity differs from its direct chelating effect on the mycob bacterial genome.
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Two new cyclic depsipeptides named swinhopeptolides A (1) and B (2) have been isolated from the marine sponge Theonella swinhoei cf. verrucosa, collected from Papua New Guinea. They each contain 11…
Identification of the Target Protein of Agelasine D, a Marine Sponge Diterpene Alkaloid, as an Anti‐dormant Mycobacterial Substance
- BiologyChembiochem : a European journal of chemical biology
- 2014
Evidence strongly suggests that the BCG3185c protein is the major target of agelasine D, and that the latter is the anti‐mycobacterial substance against dormant bacilli.
Synthesis and Bioactivity of a Cyclopolypeptide from Caribbean Marine Sponge
- Chemistry, BiologyIranian journal of pharmaceutical research : IJPR
- 2020
Newly synthesized heptacyclopeptide exhibited potent anthelmintic activity against earthworms Megascoplex konkanensis, Pontoscotex corethruses, and Eudrilus species and in comparison to standard drugs - mebendazole and piperazine citrate.
3-(Phenethylamino)demethyl(oxy)aaptamine as an anti-dormant mycobacterial substance: Isolation, evaluation and total synthesis.
- Biology, ChemistryTetrahedron letters
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Stellatolides, a new cyclodepsipeptide family from the sponge Ecionemia acervus: isolation, solid-phase total synthesis, and full structural assignment of stellatolide A.
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The first isolation, solid-phase total synthesis, and full structural assignment of a new class of cyclodepsipeptides from the Madagascan sponge Ecionemia acervus that shows in vitro cytotoxic activities at submicromolar concentrations is described.
Anti-dormant Mycobacterium bovis Produced by Indonesian’s Marine Sponge Xestospongia muta
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Based on MIC50 indicate that MIC50 from Xestospongia muta has the highest activity against Mycobacterium bovis.
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