Nda # 21-239

  • BRIEFING DOCUMENT
  • Published 2001

Abstract

Dehydroepiandrosterone [DHEA] is an endogenous substance that is the precursor to both estrogenic and androgenic hormones, including androstenedione, androstenediol, testosterone, estrogen, estradiol, and dihydrotestosterone. It is the major steroid secreted from the adrenal in humans and some other nonhuman primates, but the serum levels of this steroid… (More)

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