Navoban (tropisetron) alone and in combination with dexamethasone in the prevention of chemotherapy-induced nausea and vomiting: the Nordic experience. The Nordic Antiemetic Trial Group.

@article{Sorbe1995NavobanA,
  title={Navoban (tropisetron) alone and in combination with dexamethasone in the prevention of chemotherapy-induced nausea and vomiting: the Nordic experience. The Nordic Antiemetic Trial Group.},
  author={Bengt G Sorbe and Thomas H{\"o}gberg and Bengt Glimelius and Melanie Schmidt and L Wernstedt and H{\aa}kan B Andersson and O Hansen and Bente T. S{\o}rensen and I. R{\"a}is{\"a}nen},
  journal={Anti-cancer drugs},
  year={1995},
  volume={6 Suppl 1},
  pages={
          31-6
        }
}
To evaluate the efficacy and safety of Navoban (tropisetron) three different Nordic multicentre trials were conducted during the period 1988-92. In all, 1050 patients were recruited from 15 centres. In the first study, Navoban monotherapy was compared with a high-dose metoclopramide cocktail. In the second, Navoban +/- dexamethasone was evaluated for those patients not fully protected by Navoban alone. In the third trial, Navoban was evaluated for various chemotherapy regimens, for long-term… CONTINUE READING