Nauclea officinalis inhibits inflammation in LPS-mediated RAW 264.7 macrophages by suppressing the NF-κB signaling pathway.

@article{Zhai2016NaucleaOI,
  title={Nauclea officinalis inhibits inflammation in LPS-mediated RAW 264.7 macrophages by suppressing the NF-κB signaling pathway.},
  author={Xiao-ting Zhai and Zhiyuan Zhang and Cui-Hua Jiang and Jia-Quan Chen and Ji-Qing Ye and Xiaobin Jia and Yi Yang and Q Q Ni and Shu-xia Wang and Jie Song and Fen-xia Zhu},
  journal={Journal of ethnopharmacology},
  year={2016},
  volume={183},
  pages={159-165}
}
ETHNOPHARMACOLOGICAL RELEVANCE Nauclea officinalis has been traditionally used in China for the treatment of fever, pneumonia and enteritidis etc. This study aims to investigate effects of N. officinalis on the inflammatory response as well as the possible molecular mechanism in LPS-stimulated RAW 264.7 murine macrophage cells. MATERIALS AND METHODS Anti-inflammatory activity of N. officinalis (10, 20, 50, and 100µg/mL) was investigated by using LPS-induced RAW 264.7 macrophages. The NO… CONTINUE READING

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