Nature and distribution of sites of temperature-sensitive folding mutations in the gene for the P22 tailspike polypeptide chain.

@article{Villafane1988NatureAD,
  title={Nature and distribution of sites of temperature-sensitive folding mutations in the gene for the P22 tailspike polypeptide chain.},
  author={R. Villafane and J. King},
  journal={Journal of molecular biology},
  year={1988},
  volume={204 3},
  pages={
          607-19
        }
}
Temperature-sensitive folding (tsf) mutations in gene 9 of bacteriophage P22 interfere with the folding and association of the tailspike polypeptide chain at restrictive temperature. We report here the location and amino acid substitutions for 24 independent tsf mutants. The distribution of these and previously identified mutations is distinctly non-random; all of the 32 unambiguous sites of tsf mutations are located in the central 350 residues of the 666 residue tailspike polypeptide chain. No… Expand
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References

SHOWING 1-10 OF 40 REFERENCES
Surface amino acids as sites of temperature-sensitive folding mutations in the P22 tailspike protein.
  • 59
  • PDF
Maturation of the tail spike endorhamnosidase of Salmonella phage P22.
  • 72
...
1
2
3
4
...