Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy.

@article{Pandey2006NatureAR,
  title={Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy.},
  author={Ravindra K Pandey and Lalit N. Goswami and Yihui Chen and Amy L Gryshuk and Joseph R. Missert and Allan R. Oseroff and Thomas J. Dougherty},
  journal={Lasers in surgery and medicine},
  year={2006},
  volume={38 5},
  pages={
          445-67
        }
}
The purpose of this review is to call attention in the use of chlorophyll-a and bacteriochlorophyll-a to develop more than 600 photosensitizers (lambda (max) 660 nm-800 nm) during the last 15 years (1990-2005) at the Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo. This article mainly includes the chemistry, preclinical results, and brief clinical data of some of the most effective photosensitizers. The utility of the tumor-avid photosensitizers in developing multimodality… CONTINUE READING

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