Nature, significance, and mechanisms of electrical heterogeneities in ventricle.

@article{Poelzing2004NatureSA,
  title={Nature, significance, and mechanisms of electrical heterogeneities in ventricle.},
  author={Steven Poelzing and David S. Rosenbaum},
  journal={The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology},
  year={2004},
  volume={280 2},
  pages={
          1010-7
        }
}
Previously, dispersion of repolarization (DOR) has been extensively linked to the development of arrhythmias and sudden cardiac death. The electrical heterogeneities that cause DOR between transmural myocyte layers have been reported in a wide variety of animals and humans. The underlying causes of transmural electrical heterogeneities are in part due to heterogeneous functional expression of proteins responsible for ion handling. Recently, we found that electrophysiologic heterogeneities… CONTINUE READING
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