Naturally occurring somatostatin and vasoactive intestinal peptide inhibitors. Isolation of alkaloids from two marine sponges.

@article{Vassas1996NaturallyOS,
  title={Naturally occurring somatostatin and vasoactive intestinal peptide inhibitors. Isolation of alkaloids from two marine sponges.},
  author={Aude Vassas and G Bourdy and J J Paillard and Jacques Lavayre and Mary Pa{\"i}s and Jean Charles Quirion and C{\'e}cile Debitus},
  journal={Planta medica},
  year={1996},
  volume={62 1},
  pages={
          28-30
        }
}
The vasoactive intestinal peptide (VIP) and somatostatin (somatotropin release inhibiting factor, SRIF) are important neurotransmitters in a number of basic physiological events. Their disturbances have been reported in many diseases such as cystic fibrosis, impotent man (VIP), Alzheimer's disease, and some tumours (SRIF). Xestospongine B (1), sceptrine (2), and ageliferine (3), three alkaloids isolated from Xestospongia sp. and Agelas novaecaledoniae are reported as somatostatin and VIP… Expand
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