Naturally occurring mitochondrial DNA heteroplasmy in the MRL mouse.

@article{Sachadyn2008NaturallyOM,
  title={Naturally occurring mitochondrial DNA heteroplasmy in the MRL mouse.},
  author={Paweł Sachadyn and Xiang-Ming Zhang and Lise Desquenne Clark and Robert K. Naviaux and Ellen Heber-Katz},
  journal={Mitochondrion},
  year={2008},
  volume={8 5-6},
  pages={358-66}
}
The MRL/MpJ mouse is an inbred laboratory strain of Mus musculus, known to exhibit enhanced autoimmunity, increased wound healing, and increased regeneration properties. We report the full-length mitochondrial DNA (mtDNA) sequence of the MRL mouse (Accession # EU450583), and characterize the discovery of two naturally occurring heteroplasmic sites. The first is a T3900C substitution in the TPsiC loop of the tRNA methionine gene (tRNA-Met; mt-Tm). The second is a heteroplasmic insertion of 1-6… CONTINUE READING
Highly Cited
This paper has 96 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.
14 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

97 Citations

0204060'10'12'14'16'18
Citations per Year
Semantic Scholar estimates that this publication has 97 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…