Naturally occurring glycan forms of human immunoglobulins G1 and G2.

  title={Naturally occurring glycan forms of human immunoglobulins G1 and G2.},
  author={Gregory C. Flynn and Xiaoyu Chen and Yaoqing Diana Liu and Bhavana Shah and Zhongqi Zhang},
  journal={Molecular immunology},
  volume={47 11-12},
High resolution glycan mapping was performed on human immunoglobulin G (IgG) obtained from individual healthy subjects and from a combined sample of healthy subjects. In addition to the commonly known complex glycans, a variety of minor glycans are described and quantified, including high mannose forms and several previously unreported hybrid forms. Fc specific glycan analysis was also performed through peptide mapping with LC/MS/MS. Differences in the glycan linked Fc peptide masses allowed… CONTINUE READING
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Biologicals : journal of the International Association of Biological Standardization • 2009
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