Naturally occurring glucagon-like peptide-2 (GLP-2) receptors in human intestinal cell lines.

@article{Sams2006NaturallyOG,
  title={Naturally occurring glucagon-like peptide-2 (GLP-2) receptors in human intestinal cell lines.},
  author={Anette Sams and Sven Hastrup and Marie Frederikke Bruun Andersen and Lars Thim},
  journal={European journal of pharmacology},
  year={2006},
  volume={532 1-2},
  pages={
          18-23
        }
}
Although clinical trials with GLP-2 receptor agonists are currently ongoing, the mechanisms behind GLP-2-induced intestinal epithelial growth remain to be understood. To approach the GLP-2 mechanism of action this study aimed to identify intestinal cell lines endogenously expressing the GLP-2 receptor. Here we report the first identification of a cell line endogenously expressing functional GLP-2 receptors. The human intestinal epithelial cell line, FHC, expressed GLP-2 receptor encoding mRNA… CONTINUE READING

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