Naturally occurring compensated insulin resistance selectively alters glucose transporters in visceral and subcutaneous adipose tissues without change in AS160 activation.

@article{Waller2011NaturallyOC,
  title={Naturally occurring compensated insulin resistance selectively alters glucose transporters in visceral and subcutaneous adipose tissues without change in AS160 activation.},
  author={Allyson Waller and Katharina Kohler and Tara Ann Burns and Margaret C. Mudge and J Belknap and V{\'e}ronique A. Lacombe},
  journal={Biochimica et biophysica acta},
  year={2011},
  volume={1812 9},
  pages={1098-103}
}
Although the importance of adipose tissue (AT) glucose transport in regulating whole-body insulin sensitivity is becoming increasingly evident and insulin resistance (IR) has been widely recognized, the underlying mechanisms of IR are still not well understood. The purpose of the present study was to determine the early pathological changes in glucose transport by characterizing the alterations in glucose transporters (GLUT) in multiple visceral and subcutaneous adipose depots in a large animal… CONTINUE READING