Naturally occurring anti-alpha-galactosyl antibodies: relationship to xenoreactive anti-alpha-galactosyl antibodies.

@article{Parker1999NaturallyOA,
  title={Naturally occurring anti-alpha-galactosyl antibodies: relationship to xenoreactive anti-alpha-galactosyl antibodies.},
  author={William Parker and Shu S. Lin and Paul B Yu and Anjuli Sood and Youji Nakamura and Andong Song and Mary Lou Everett and Jeffrey L Platt},
  journal={Glycobiology},
  year={1999},
  volume={9 9},
  pages={865-73}
}
Antibodies produced by an individual without a known history of sensitization to the relevant antigen are called "natural" antibodies. Some natural antibodies, called xenoreactive antibodies, react with the cells of foreign species. Most xenoreactive antibodies in humans and higher primates bind to a nonreducing terminal galactose expressed by pigs and other lower mammals. Although human natural antibodies which bind to one or more of a variety of terminal alpha-galactosyl structures have been… CONTINUE READING

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