Naturally occurring Tyzzer's disease and intestinal spirochetosis in guinea pigs.

@article{Zwicker1978NaturallyOT,
  title={Naturally occurring Tyzzer's disease and intestinal spirochetosis in guinea pigs.},
  author={Gallus Zwicker and Gerald E Dagle and R R Adee},
  journal={Laboratory animal science},
  year={1978},
  volume={28 2},
  pages={193-8}
}
Bacillus piliformis infection (Tyzzer's disease) occurred in two young guinea pigs, causing unthriftiness and diarrhea which resulted in death. There was necrosis and inflammation of the ileum, cecum, and colon. Intestinal epithelial cells contained organisms resembling Bacillus piliformis. Spirochetes were found in the cecum and colon, mainly in crypts. Acute diarrhea occurred in another guinea pig which became cachetic and was killed. Histologically, large numbers of spirochetes were present… CONTINUE READING

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