Naturally occurring α-synuclein autoantibody levels are lower in patients with Parkinson disease.

Abstract

OBJECTIVE Biomarkers are required for the diagnosis and monitoring of disease progression in Parkinson disease (PD). To date, most studies have concentrated on α-synuclein (α-Syn), a protein involved in Parkinson disease pathogenesis, as a potential biomarker, with inconsistent outcomes. Recently, naturally occurring autoantibodies against α-Syn (α-Syn-nAbs… (More)
DOI: 10.1212/WNL.0b013e31827b90d1

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