Natural variation within the principal arginine-specific protease gene, prpR1, of Porphyromonas gingivalis.

@article{Allaker1997NaturalVW,
  title={Natural variation within the principal arginine-specific protease gene, prpR1, of Porphyromonas gingivalis.},
  author={Robert Patrick Allaker and Joseph Aduse-Opoku and Jay Batten and Michael A. Curtis},
  journal={Oral microbiology and immunology},
  year={1997},
  volume={12 5},
  pages={
          298-302
        }
}
RI, one of the major extracellular arginine-specific proteases of Porphyromonas gingivalis is a heterodimer composed of catalytic (alpha) and adhesin (beta) chains, encoded by the gene prpR1. The distribution of prpR1 and its variation within 43 isolates of P. gingivalis was determined. Chromosomal DNA was digested with Sma I and probed with a 32P-labeled DNA fragment from within the coding region for the alpha component of P. gingivalis W50. All isolates gave the expected 3.2 kb band… CONTINUE READING

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