Natural variation in a Drosophila clock gene and temperature compensation.

  title={Natural variation in a Drosophila clock gene and temperature compensation.},
  author={Lesley A Sawyer and Jill M. Hennessy and Alexandre Afr{\^a}nio Peixoto and Ezio Rosato and Howard Parkinson and Rodolfo Costa and Charalambos P Kyriacou},
  volume={278 5346},
The threonine-glycine (Thr-Gly) encoding repeat within the clock gene period of Drosophila melanogaster is polymorphic in length. The two major variants (Thr-Gly)17 and (Thr-Gly)20 are distributed as a highly significant latitudinal cline in Europe and North Africa. Thr-Gly length variation from both wild-caught and transgenic individuals is related to the flies' ability to maintain a circadian period at different temperatures. This phenomenon provides a selective explanation for the… CONTINUE READING

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