Natural transfer of sulphonamide and ampicillin resistance between Escherichia coli residing in the human intestine.

@article{Trobos2009NaturalTO,
  title={Natural transfer of sulphonamide and ampicillin resistance between Escherichia coli residing in the human intestine.},
  author={Margarita Trobos and Camilla H. Lester and John Elmerdahl Olsen and Niels Frimodt-M\oller and Anette Marie Hammerum},
  journal={The Journal of antimicrobial chemotherapy},
  year={2009},
  volume={63 1},
  pages={80-6}
}
OBJECTIVES The aim of this study was to investigate whether the sulphonamide resistance gene sul2 could be transferred between Escherichia coli in the human gut. METHODS Nine volunteers ingested a 10(9) cfu suspension of sulphonamide-susceptible, rifampicin-resistant E. coli recipients of human origin. Three hours later, they ingested a 10(7) cfu suspension of a sulphonamide-resistant (MIC>1024 mg/L) E. coli donor of pig origin. Stool samples were collected 24 h prior to ingestion, daily for… CONTINUE READING

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