Natural surfactant-based topical vehicles for two model drugs: Influence of different lipophilic excipients on in vitro/in vivo skin performance.

@article{Savi2009NaturalST,
  title={Natural surfactant-based topical vehicles for two model drugs: Influence of different lipophilic excipients on in vitro/in vivo skin performance.},
  author={Sne{\vz}ana D Savi{\'c} and Christian Weber and Miroslav M. Savi{\'c} and Christel Charlotte M{\"u}ller-Goymann},
  journal={International journal of pharmaceutics},
  year={2009},
  volume={381 2},
  pages={
          220-30
        }
}

NEW NATURAL SUGAR-BASED SURFACTANTS INTENDED FOR STABILIZATION OF COSMETIC/DERMOPHARMACEUTICAL VEHICLES – SAFETY AND EFFICACY ASSESSMENT

Investigating the most frequently used APG, that emulsions based on these emulsifiers could probably be promoted as safe cosmetic/ dermopharmaceutical vehicles showed an excellent skin moisturizing capacity which is essential in maintaining healthy skin, but also in improving dermatitis, which follows most pathological skin conditions.

N EW NATURAL SUGAR-BASED SURFACTANTS INTENDED FOR STABILIZATION OF COSMETIC/DERMOPHARMACEUTICAL VEHICLES - SAFETY AND EFFICACY ASSESSMENT

Investigating the most frequently used APG, that emulsions based on these emulsifiers could probably be promoted as safe cosmetic/ dermopharmaceutical vehicles showed an excellent skin moisturizing capacity, which is essential in maintaining healthy skin, but also in improving dermatitis, which follows most pathological skin conditions.

Studies on Improving Solubility in Different Media for Said Formulations with Topical Application

The solubilization tests performed for pharmaceutical compounds of the NSAID class in different hydrophilic media are presented and help in choosing solvents in the formulation and technologicalization of semi-solid preparations with topical application.

From conventional towards new – natural surfactants in drug delivery systems design: current status and perspectives

Recent FDA certification of an alkyl polyglucoside surfactant for topical formulation presents a significant step in the process of recognition of this relatively new group of surfactants, which could trigger further research into the potential benefits of naturally derived materials in both conventional and new drug delivery systems.

Stability and In Vitro Skin Compatibility of an Adapalene-Loaded Solid Lipid Microparticle Dispersion

A novel adapalene-loaded solid lipid microparticle (SLMA) dispersion composed of topically approved ingredients exhibited follicular penetration and a targeted drug release in sebum. In the present

Systematic Investigation of the Effect of Non-Ionic Emulsifiers on Skin by Confocal Raman Spectroscopy—A Comprehensive Lipid Analysis

It is possible to characterize the molecular effects of non-ionic emulsifiers on skin lipids and further deepen the understanding of enhancing substance penetration with reduced skin barrier properties and increased lipid fluidity.

Lactobionic acid as antioxidant and moisturizing active in alkyl polyglucoside‐based topical emulsions: the colloidal structure, stability and efficacy evaluation

Good physical stability and applicative characteristics were obtained although LA strongly influenced the colloidal structure of the vehicle, and LA per se and in APG‐based emulsion showed satisfying antioxidant activity that promotes it as mild multifunctional cosmeceutical efficient in the treatment and prevention of the photoaged skin.

Influence of internal structure and composition of liquid crystalline phases on topical delivery of paclitaxel.

LP-20 provides optimization of paclitaxel cutaneous delivery and efficient cytotoxicity and is demonstrated to be effective against fibroblasts and drug release differences.

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