Natural progression of untreated hepatolithiasis that shows no clinical signs at its initial presentation.

@article{Kusano2001NaturalPO,
  title={Natural progression of untreated hepatolithiasis that shows no clinical signs at its initial presentation.},
  author={Toshiomi Kusano and Tadashi Isa and Mitsuji Ohtsubo and Tomoko Yasaka and Masato Furukawa},
  journal={Journal of clinical gastroenterology},
  year={2001},
  volume={33 2},
  pages={114-7}
}
GOALS To elucidate the natural progression of hepatolithiasis that showed no signs at the time of initial presentation. STUDY Over a 17-year period, we observed 122 of 311 patients with hepatolithiasis who reported no symptoms and, thus, who received no treatment at initial presentation. The follow-up period was for up to 15 years (mean, 10.08 years). RESULTS Fourteen of 112 patients (11.5%) developed some symptoms attributed to hepatolithiasis. The interval until the onset of symptoms… CONTINUE READING

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