Natural products from environmental DNA hosted in Ralstonia metallidurans.


Metagenomic studies designed to access new small molecules from the heterologous expression of environmental DNA have focused on the use of two model systems, Escherichia coli and Streptomyces spp., as heterologous hosts. Accessing the biosynthetic potential of DNA extracted from the bacteria present in environmental samples will require the development of… (More)
DOI: 10.1021/cb8002754


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