Natural products as sources of new drugs over the last 25 years.

@article{Newman2007NaturalPA,
  title={Natural products as sources of new drugs over the last 25 years.},
  author={David J. Newman and Gordon M. Cragg},
  journal={Journal of natural products},
  year={2007},
  volume={70 3},
  pages={461-77}
}
This review is an updated and expanded version of two prior reviews that were published in this journal in 1997 and 2003. In the case of all approved agents the time frame has been extended to include the 251/2 years from 01/1981 to 06/2006 for all diseases worldwide and from 1950 (earliest so far identified) to 06/2006 for all approved antitumor drugs worldwide. We have continued to utilize our secondary subdivision of a "natural product mimic" or "NM" to join the original primary divisions… CONTINUE READING
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