Natural products as platforms for the design of sphingolipid-related anticancer agents.

@article{Delgado2013NaturalPA,
  title={Natural products as platforms for the design of sphingolipid-related anticancer agents.},
  author={Alberto {\'A}lvarez Delgado and Gemma Fabrias and Jos{\'e}M. Casas and Jose L. Abad},
  journal={Advances in cancer research},
  year={2013},
  volume={117},
  pages={
          237-81
        }
}
Modulation of sphingolipid metabolism is a promising strategy for cancer therapy that has already opened innovative approaches for the development of pharmacological tools and rationally designed new drugs. On the other hand, natural products represent a classical and well-established source of chemical diversity that has guided medicinal chemists on the development of new chemical entities with potential therapeutic use. Based on these premises, the aim of this chapter is to provide the reader… CONTINUE READING
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