Natural microbe-mediated refractoriness to Plasmodium infection in Anopheles gambiae.

  title={Natural microbe-mediated refractoriness to Plasmodium infection in Anopheles gambiae.},
  author={Chris M. Cirimotich and Yuemei Dong and April M. Clayton and Simone L. Sandiford and Jayme Augusto Souza-Neto and Musapa Mulenga and George Dimopoulos},
  volume={332 6031},
Malaria parasite transmission depends on the successful transition of Plasmodium through discrete developmental stages in the lumen of the mosquito midgut. Like the human intestinal tract, the mosquito midgut contains a diverse microbial flora, which may compromise the ability of Plasmodium to establish infection. We have identified an Enterobacter bacterium isolated from wild mosquito populations in Zambia that renders the mosquito resistant to infection with the human malaria parasite… CONTINUE READING
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