Natural killer cells may be the only cells in normal mouse lymphoid cell populations endowed with cytolytic ability for antibody-coated tumour target cells.

@article{Ojo1978NaturalKC,
  title={Natural killer cells may be the only cells in normal mouse lymphoid cell populations endowed with cytolytic ability for antibody-coated tumour target cells.},
  author={E A Ojo and Hans Wigzell},
  journal={Scandinavian journal of immunology},
  year={1978},
  volume={7 4},
  pages={297-306}
}
Mouse normal lymphoid cells were analysed as to their ability to perform in three cytolytic systems: Ability to act as 'natural killer', NK, cells against a NK sensitive tumour target, YAC; as effector cells against IgG-coated 815 cells, or to function as effector cells against IgG-coated CRBC. NK activity and ADCC against the IgG-coated P815 cells were found to vary in parallel as affected by age, organ distribution and genotype of the effector cells. On the other hand, ADCC against CRBC was… CONTINUE READING

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