Natural killer cells in pregnancy and recurrent pregnancy loss: endocrine and immunologic perspectives.

@article{Dosiou2005NaturalKC,
  title={Natural killer cells in pregnancy and recurrent pregnancy loss: endocrine and immunologic perspectives.},
  author={Chrysoula Dosiou and Linda C. Giudice},
  journal={Endocrine reviews},
  year={2005},
  volume={26 1},
  pages={44-62}
}
The endocrine system and the immune system interact closely during implantation and maintenance of pregnancy. One of the most striking examples of this communication is at the level of the decidua (endometrium of pregnancy). Here, under the influence of sex steroids, there is a dramatic increase of a unique population of lymphocytes, the uterine natural killer (uNK) cells, in early pregnancy. These cells derive predominantly from a subset of peripheral blood NK cells, which under hormonal… CONTINUE READING