Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners.

@article{Radaeva2006NaturalKC,
  title={Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners.},
  author={Svetlana Radaeva and Rui Sun and Barbara Jaruga and Van Thi-Thuy Nguyen and Zhigang Tian and Bin Gao},
  journal={Gastroenterology},
  year={2006},
  volume={130 2},
  pages={435-52}
}
BACKGROUND & AIMS Viral hepatitis infection, which is a major cause of liver fibrosis, is associated with activation of innate immunity. However, the role of innate immunity in liver fibrosis remains obscure. METHODS Liver fibrosis was induced either by feeding mice with the 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC) diet or by injecting them with carbon tetrachloride. The Toll-like receptor 3 ligand, polyinosinic-polycytidylic acid, was used to activate innate immunity cells and… CONTINUE READING
Highly Influential
This paper has highly influenced 23 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 176 extracted citations

Toll-Like Receptor Signaling and Liver Fibrosis

Gastroenterology research and practice • 2010
View 6 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…