Natural killer cell biology: an update and future directions.

  title={Natural killer cell biology: an update and future directions.},
  author={Kerry S. Campbell and Jun Hasegawa},
  journal={The Journal of allergy and clinical immunology},
  volume={132 3},
Natural killer (NK) cells constitute a minor subset of normal lymphocytes that initiate innate immune responses toward tumor and virus-infected cells. They can mediate spontaneous cytotoxicity toward these abnormal cells and rapidly secrete numerous cytokines and chemokines to promote subsequent adaptive immune responses. Significant progress has been made in the past 2 decades to improve our understanding of NK cell biology. Here we review recent discoveries, including a better comprehension… CONTINUE READING
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